I think you'll find that most of them require a combination of time and mileage tuning to develop an accurate reading for actual mpg.
They are good for indicating the engine efficiency in real time.
I find the best calculator for mpg being the actual miles/amount of fuel used method.
As long as you adhere to the method of tracking the actual miles and filling the tank allowing the nozzle to click off as the "full indicator" it will be true.
If you are looking for average mpg then tank to tank will work, if you are looking for highway mpg you'll want to fill your tank, check your odometer, do your highway run, then refill with ending odometer reading. That will give you the short answer on highway response.
I've learned not to trust the computers until the agree with the real numbers.
Karl Fortner
Tacoma, Wa.
Gadgetman Tacoma