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Pre-Groove Prep is always a smart idea to ensure that the groove "takes" right from the start, and re-routing the PCV and/or opening the gaps now will give you some small benefit. But before we go down those roads, given the age of this vehicle, how are the tranny and diff fluids - when was the last time they were changed? (the synthetics they're using now are quite good for efficiency) what about the gaskets/hoses - any leaky ones?
How about the upstream oxygen sensor(s) and catalytic converter(s)? O2s need replacing every 60k-100k Miles, and converters melt/get clogged. Oh, the cooling system - when was the last time that was flushed and the cap and T-stat replaced? How's the battery/alternator/charging system/grounds? If these things can't be checked off as taken care of (maintained), you might run up hard against them when you do get the groove on...as I'm sure you recall advising your clients when you were working as a mechanic.
I've found that engines need PCV/blowby vapours, so rather than letting them vent, I've re-routed the hose to where the factory breather gets it's source of clean air on the intake tube, after the MAF and filter...but my "valve" was simply an orifice tube. if yours is an actual check valve that is held open by manifold vacuum, you'll need to find a fitting that isn't restrictive. another thing I've done on mine is open up the diameter of the hoses, from whatever the factory diameter was to 3/4" - if the factory helped those vapours to move with some vacuum, by removing the vacuum, you'll have to open up the road so they can move just as easily, right? (another difference between our method and stock is that we encourage those vapours to move when they're being made most - when the throttle plate is more open under a power demand - rather than constantly, except when manifold vac drops at high demand time. The engineers have it bass ackwards, don't you think?)
Spark plug gap - when was the last time you did a traditional tune up on this truck? plugs, wires, (coil/cap/rotor?), air filter, cleaned the MAF...
To me, it's most important to get as much of the ignition energy the coil makes to the spark gap as possible, and that means replacing used wires with new ones with as low resistance as possible. They are NOT all the same, as I'm sure you know, and I am a convert to the Granatelli wires that are zero resistance or as close to it as we can come without needing to operate at absolute zero. Call Granatelli Direct - they gave me the price they charge their distributors (like Summit) when I did. once you get all the energy going to where it belongs, then you can worry about the gap...and yes, you can make it much bigger than what the factory engineers specify when you make sure the energy gets to where it belongs
All of this should give you some time to yourself once the kids are in bed and responsibility handed off to the wife...